Biodegradation of Tetralin: Genomics, Gene Function and Regulation
نویسندگان
چکیده
منابع مشابه
Genetic analysis of biodegradation of tetralin by a Sphingomonas strain.
A strain designated TFA which very efficiently utilizes tetralin has been isolated from the Rhine river. The strain has been identified as Sphingomonas macrogoltabidus, based on 16S rDNA sequence similarity. Genetic analysis of tetralin biodegradation has been performed by insertion mutagenesis and by physical analysis and analysis of complementation between the mutants. The genes involved in t...
متن کاملMicrobial computational genomics of gene regulation*
Escherichia coli is a free-living bacterium that condensates a large legacy of knowledge as a result of years of experimental work in molecular biology. It represents a point of departure for analyses and comparisons with the ever-increasing number of finished microbial genomes. For years, we have been gathering knowledge from the literature on transcriptional regulation and operon organization...
متن کاملThnY is a ferredoxin reductase-like iron-sulfur flavoprotein that has evolved to function as a regulator of tetralin biodegradation gene expression.
Previous genetic studies in Sphingomonas macrogolitabida strain TFA have established that expression of genes involved in tetralin biodegradation (thn genes) requires the function of the LysR type activator ThnR and also ThnY. Sequence comparison indicated that ThnY is homologous to bacterial oxygenase-coupled NAD(P)H-dependent ferredoxin reductases. However, ThnY showed substitutions in highly...
متن کاملGene regulation, evolvability and the limits of genomics
Of the fundamental issues in biology that remain unresolved, one of the most prominent is that of the evolution of gene expression. Unlike proteins, in which conservation of function is largely reflected in conservation of primary sequence, conservation of function in the regulatory regions of genes seems to be maintained in the face of quite widely divergent primary sequence. Since the diversi...
متن کاملBiodegradation Database: specialized metabolism for functional genomics
The University of Minnesota Biocatalysis/Biodegradation Database (UM-BBD, http://www.labmed.umn.edu/ umbbd/index.html ) first became available on the web in 1995 to provide information on microbial biocatalytic reactions of, and biodegradation pathways for, organic chemical compounds, especially those produced by man. Its goal is to become a representative database of biodegradation, spanning t...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Genes
سال: 2019
ISSN: 2073-4425
DOI: 10.3390/genes10050339